Identifikasi Kandungan Senyawa Kimiawi Psidium Guajava Linn. dan Anacardium Occicentale Linn. dan Efeknya terhadap Penyembuhan Luka pada Mus Musculus Linn.

Fitri Nirwana Hasibuan

Abstract


The aims of this research is to identify the types of chemical compounds that have the most role in wound treatment in mice (Mus musculus Linn.) using guava leaves (Psidium guajava Linn.) and cashew nuts (Anacardium occidentale Linn.). Based on TLC (Thin Layer Chromatography) analysis, the compounds contained in guava leaves and cashew leaves are flavonoids, saponins, tannins and alkaloids with a significant effect on wound treatment in mice. The amount of chemical compounds in guava leaves was 35.105 ppm, 31.508 ppm,

9.400 ppm and 1.985 ppm, respectively. While in cashew leaves 42.752 ppm, 31.616 ppm, 8,001 and 1,832 ppm.


Keywords


Wound treatment, Psidium guajava leaf, Anacardium occidentale leaf, Biofarmaka, Etnobatanical.

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References


Carey, F. A. (2006). Organic Chemistry. 6th ed. New York: McGraw Hill, 954. Chanwitheesuk, A. Teerawutgulrag A. and Rakariyatham N. (2004). Screening of Antioxidant Activity and Antioxidant Compounds of Some Edible Plants of Thailand. Food Chemistry.92, 491-497. Fitriyah, L. (2002). Pengaruh Getah Pohon Pisang Ambon (Musa acuminate, Linn.) terhadap Waktu Pendarahan, Koagulasi dan Penutupan Luka Pada Mencit (Mus musculus Linn.). Program Studi Biologi. Universitas Islam Sunan Kalijaga. Yogyakarta. Skripsi. Lorena. C, Asma. R, Maria. L.S. (2021). Bioactives from Psidium guajava Leaf decoction: LC-HRMS-MS-Qtof Identification, bioactivities and bioavailability evaluation. Food Chemistry Advances 1 (2022). https://doi.org/10.1016/j.focha.2021.10000. Lathifah, Q. (2008). Uji Efektifitas Ekstrak Kasar Senyawa Antibakteri pada Buah Belimbing Wuluh (Averrhoa bilimbi L.) dengan Variasi Pelarut. Jurusan Kimia Fakultas Sains dan Teknologi. Universitas Islam Negeri (UIN) Malang. Metwally, A.M., Omar, A.A., Harraz, F.M., El Sohafy, S.M., (2010). Phytochemical investigation and antimicrobial activity of Psidium guajava L. leaves. Pharmacogn. Mag. 6 (23), 212–218. https://doi. org/10.4103/0973-1296.66939 Nirwana, F. (2015). Efek Daun Jambu Biji (Psidium guajava Linn.) dan Daun Jambu Mete (Anacardium occidentale Linn.). Majalah Obat TRadisional UGM. Vol 20. No.1. https://doi.org/10.22146/tradmedj.7747. Sharma, A.K, Mayank Gangwar, Ragini Tilak, Gopal Nath, Akhoury Sudhir Kumar Sinha, Yamini Bhusan Tripahthi, Dharmendra Kumar. 2012. Comparative in vitro Antimicrobial and Phytochemical Evaluation of Mathenolic Extract of Root, Stem and Leaf of Jatropa cucas Linn. Pharmacognosy J. https://doi.org/10.5530/pj.2012.30.7. Sutrisna, EM. 2016. Herbal Medicine. Surakarta. Muhammadiyah University Press. Ugbogu, E.A, Okezie Emmanuel, Miracle Ebubechi, Uche, Emmanuel Dike Dike dkk. 2022. The Ethnobotanical, Phytochemistry and Pharmacological Activities of Psidium guajava Linn. Arabian Journal of Chemistry (2022) 15, 103759. King Saud University. https://doi.org/10.1016/j.arabjc.2022.103759. Zhou. G, Jiaming Zhao, Chang Gong, Jixuan Xu, Ce Song, Dali Meng. (2022). Chemical Constituents from the leaves of Psidium guajava linn. And their chemotaxonomic significance. Natural Product Research. 5 februari 2022. https://doi.org/10.1080/14786419.2021.1963245.


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